Publications

Google Scholar

• Leduc, Andrew, and Nikolai Slavov. "Protein degradation and growth dependent dilution substantially shape mammalian proteomes." bioRxiv (2025): 2025-02. [Preprint]
• Leduc, A., et al. Limiting the impact of protein leakage in single-cell proteomics bioRxiv. doi.org/10.1101/2024.07.26.605378 [Preprint]
• Derks, J., Leduc, A., et al. Single-nucleus proteomics identifies regulators of protein transport. bioRxiv. doi.org/10.1101/2024.06.17.599449 [Preprint]
• Lin, B., Shah, V.S., Chernoff, C., Leduc, A. et al. Airway hillocks are injury-resistant reservoirs of unique plastic stem cells. Nature (2024). https://doi.org/10.1038/s41586-024-07377-1 [Paper]
• Leduc, A., Koury, L., Cantlon, J., Slavov, N., (2023) Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP. Nature Protocols. doi.org/10.1038/s41596-024-01033-8 [Paper] [Preprint]
• Leduc, A., Harens, H., Slavov, N., (2023) Modeling and interpretation of single-cell proteogenomic data. arxiv. doi.org/10.48550/arXiv.2308.07465 [Preprint]
• Montalvo, A., Gruskin, Z., Leduc, A., Liu, M., Gao, Z., Ahn, J., Straubhaar, J., Slavov, N., Alvarez-Dominguez, J., (2023) An adult clock component links circadian rhythms to pancreatic Beta-cell maturation. biorxiv. doi.org/10.1101/2023.08.11.552890 [Preprint] [Website]
• Wallmann, G., Leduc, A., & Slavov, N. (2023). Data-Driven Optimization of DIA Mass-Spectrometry by DO-MS. Journal of Proteome Research 2023 22 (10), 3149-3158 DOI: 10.1021/acs.jproteome.3c00177 [Journal] [Preprint]
• Leduc, A., Huffman, R. G., Cantlon, J., Khan, S., & Slavov, N. (2022). Exploring functional protein covariation across single cells using nPOP. Genome Biology, 23(1), 1-31. [Journal] [Website]
• Gatto, L., Aebersold, R., Cox, J., Demichev, V., Derks, J., Leduc, A. Emmott, E., ... & Slavov, N. (2022). Initial recommendations for performing, benchmarking, and reporting single-cell proteomics experiments. Nature Methods [Journal] [Preprint]
• Derks, J., Leduc, A., Wallmann, G., Huffman, R. G., Willetts, M., Khan, S., ... & Slavov, N. (2022). Increasing the throughput of sensitive proteomics by plexDIA. Nature Biotechnology, 1-10. [Journal] [Website]
• Huffman, R. G., Leduc, A., Wichmann, C., di Gioia, M., Borriello, F., Specht, H., ... & Slavov, N. (2022). Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages. Nature Methods, 1-10. [Preprint] [Website]
• Petelski, A. A., Emmott, E., Leduc, A., Huffman, R. G., Specht, H., Perlman, D. H., & Slavov, N. (2021). Multiplexed single-cell proteomics using SCoPE2. Nature protocols, 16(12), 5398-5425. [Journal]
• *Wehrman, M. D., *Leduc, A., Callahan, H. E., Mazzeo, M. S., Schumm, M., & Schultz, K. M. (2018). Rheological properties and structure of step and chain growth gels concentrated above the overlap concentration. AIChE Journal, 64(8), 3168-3176. [Journal]